CHOzen - Canton Biologics

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Services & Solutions

R&D

Antibody Discovery Developability Assessment

Development

Cell Line

Cell Line Development High-Efficiency Expression Vector

Process Analytical Methods Microbial CGT

Manufacturing

Tech Transfer Drug Substance Drug Product Process Characterization Process Validation

Quality & Support

Quality Control Quality Assurance Regulatory Affairs Project Management IP Management

Animal Health

Case Studies & Experience

Technology Platforms

Cell Line Platform

CHOzen® CHOFlow® GS-KO GlycoExpress® Other Commercial Cell Lines Canvector®

Process Development Platform

CHO-Rise® CBoost® CanPure™ Purification Platform CanCapture™ Membrane Chromatography Platform CanConcentra™ High-Concentration Formulation Platform

Manufacturing Platform

Scale-Plus Technology Biologics Pulsing Production Line

IgMaxTM

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类别产品类型领域

CHOzen®

Global Leading Biologics Development Technologies

Commercializable Cell Lines

CHOzen®

CHO-K1 Cell Line Derived from ECACC

CHOFlow®

Fucosyltransferase 8 Knockout CHOzen Cell Line

CHOzen GS

Glutamine Synthetase Knockout CHOzen Cell Line

GlycoExpress®

Human Myeloid Leukemia Cell Line

Other Commercial Cell Lines

HEK293(T), CHO-DG44, CHO-DXB11, NS0, SP2/0, E. coli

High-Efficiency Expression Vectors

Canvector® IgFlex ™

Suitable for Multiple Protein Structures

IgMax®

Engineered Vector Designed for IgM

DTEasy ™

Specialized Vector for Proteins with Complex Folding or Unstable Structures

Proprietary Media

CHO-Rise® /Plus

Proprietary Formulation, Localized Production, Significantly Reduced Costs

Other Animal Cell Culture Medium

CHO-K1 Transient Expression Medium, Customized Media for Quality Control

Transmission

Chassis

Engine

Expression Level Increased Up to 200 Times

Average Monoclonal Antibody Expression > 8 g/L (up to 39 g/L)

Helping Clients Reducing Production Costs

Specializing in Difficult-to-Express (DTE) Proteins

CHOzen®

Stable and High-Producing CHO Cell Expression System with Broad Compatibility

High-Producing Host Compatible with VariousMolecules

Possesses Good Scale-up Capability

Original License

Official authorization from ECACC (European Collection of Authenticated Cell Cultures) under Public Health England, where global rights are held by the European branch of Canton Biologics

Endorsement by Leading Companies

Widely adopted by global leading enterprises such as Zoetis(formerly Pfizer Animal Health), Novo Nordisk, and Regeneron

Stable and High-Producing

Batch yield up to 39g/L, with outstanding large-scale scaling -up capability

Product Family

Multiple modified lines such as CHO K1 wild-type, GS-knockout, and fucose-knockout

Broad Compatibility

Excellently expresses various products such as monoclonal antibodies, bispecific antibodies, and recombinant proteins

・CHOzen® performs excellently in different molecules and has a significant improvement compared with the industry level.
・The enhanced process also shows excellent performance in commercial scale - up.